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Furthermore, the activation of EPAC2 stimulates the release of calcium from the endoplasmic reticulum, which raises intracellular calcium levels and promotes exocytosis

5 Cawley J, Meyerhoefer C

doi: van der Schoot, A., Drysdale, C., Whelan, K

Studies show that in some cases, GLP-1 drugs can cause gastroparesis, a condition where the stomach doesnt empty properly, leading to severely delayed digestion and awful side effects