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Rubbing is not

We often see a higher level of food sensitivities of the foods most commonly consumed which indicates that those food proteins are leaking through the gut and into the bloodstream

J Am Acad Dermatol 1990

Nevertheless, because lysine conjugation operates under mild conditions and does not require genetic engineering of the antibody, it remains one of the important strategies for constructing ADCs, especially as site-specific linker technologies are revitalizing the application of lysine in the ADC field