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Wegovy also slows gastric emptying, meaning food remains in the stomach for longer periods, promoting feelings of fullness and reducing overall caloric intake

The safety profile remains consistent with shorter term studies

Research findings on glucose homeostasis [6] : Oral glucose tolerance testing showed no negative impact on glucose levels in human subjects No insulin sensitivity changes following chronic exposure Fat-reducing effects occur without inducing insulin resistance Avoids common metabolic complications associated with hGH therapy This metabolic selectivity positions the peptide as targeting adipose tissue lipid metabolism without broader endocrine disruption affecting growth, glucose regulation, or protein synthesis

2016 Nov Jacob Joseph, Joseph Loscalzo