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[1] Around 2030% of East Asians carry the rs671 (ALDH2*2) allele on chromosome 12, which results in a less functional acetaldehyde dehydrogenase enzyme, responsible for the breakdown of acetaldehyde, and accounts for most incidents of alcohol flush reaction worldwide

We see this in regards to reducing the pleasure-seeking around alcohol, nicotine, and potentially sex drives. The evidence surrounding changed sexual function is limited, and mixed

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