Theres no one answer to this question, because a lot depends on a persons metabolism, starting weight, and lifestyle
GLP-1s have a plethora of benefits ranging from reducing inflammation, to stimulating the immune system, to reducing oxidative stress, to boosting mitochondrial function, that lead to documented neurocognitive and cardiovascular protection
Naunyn-Schmiedebergs Arch Pharmacol 392:13211330 Zatorski H, Salaga M, Zieliska M, Mokrowiecka A, Jacenik D, Krajewska WM, Maecka-Panas E, Fichna J (2021) Colonic inflammation induces changes in glucose levels through modulation of incretin system
When these vessels become blocked or damagedwhether due to diabetes, hypertension, or other factorsthe oxygen-starved retinal tissue can deteriorate, leading to irreversible vision impairment