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The body's ability to produce and recycle glutathione lowers with age and is even affected by external stressors like poor diet, pollution, UV exposure, and lifestyle habits such as smoking and excessive alcohol consumption

The biosynthesis of carnitine is a complex process that involves multiple enzymatic steps and is tightly regulated to ensure cellular energy homeostasis

Life expectancy rises, and Americans spend fewer years living with chronic diseases like diabetes

We further discuss how TAM-derived cytokines, lipid mediators, and iron-handling proteins orchestrate a microenvironment that either promotes or restrains ferroptotic cell death