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By expanding our search to include non-published studies, it is possible we may have found more instances of null results

A 2013 study, for example, found that activity (measured using PET scans of glucose metabolism, a popular way to gauge action in the brain) in two key areas was much lower in the brains of frequent ecstasy users than it was in the brains of people who rarely or never used

Hammond D, et al

It can increase the chance of false positives or real elevations in tumor markers, such as: Carcinoembryonic antigen (CEA) CYFRA 21-1 Neuron-specific enolase (NSE) When this happens, it can lead to over-testing or early cancer screening