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When GHK encounters copper ions under appropriate conditions, the peptide acts as a multidentate ligand , binding the metal through multiple donor atoms to form the well-characterized GHK-Cu complex

When H 2 O 2 increases there are several effects on one-carbon metabolism

Nelson JL, Bernstein PS, Schmidt MC, Von Tress MS, Askew EW: Dietary modification and antioxidant supplementation differentially affect serum carotenoids, antioxidant levels and markers of oxidative stress in older humans

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