Considering the good quality of Cochrane reviews, we did not analyze the original clinical studies included in the SRs, but focused on summarizing intervention data from SRs using the existing meta-analysis with GRADE, while also analyzing potential mechanisms underlying different interventions within each review (details provided in Supplementary file Table 4)
Without a wound, an active lesion, or another mucous-membrane breach, there is nowhere for the pathogen to set up an infection
This product is intended for use by persons of legal age or older, and not by children, women who are pregnant or breast feeding or persons with or at risk of heart disease, high blood pressure, diabetes or taking medicine for depression or asthma
Cultured cells and animal models exposed to EC fluids and aerosols show increased oxidative stress, inflammatory responses, and impaired pulmonary defenses that may contribute to adverse health effects 6,7,8,9