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Recent research shows that EGCG has therapeutic potential in various neurodegenerative disorders, with distinct mechanisms tailored to each conditions pathophysiology

The extract also contains caffeine, which decreases appetite ( Effectiveness: A recent study in people with metabolic syndrome showed that those taking 400 mg of green coffee bean extract per day experienced a significant decrease in waist circumference and appetite compared to a placebo group ( An analysis of three studies found that overweight participants who took either 180 or 200 mg per day of green coffee extract for up to 12 weeks experienced an average weight loss of 6 pounds (2.47 kg) more than those taking placebos ( Side effects: Though green coffee bean extract is generally well tolerated, it may cause headaches and increased heart rate in some people

The synergy between the two pathways is what makes the combination dosing more efficient per unit of compound